New CRISPR Class Expands Genetic Engineering Toolbox

ILLUSTRATIONS REPRESENTING THE COMPONENTS OF THE COMMON DCAS9 SYSTEM (TOP) AND THE CASCADE SYSTEM (BOTTOM)

In a recent study, Charles Gersbach and Adrian Oliver, a post-doctoral fellow in the Gersbach lab who led the project, describe how they successfully harnessed Class 1 CRISPR systems to turn target genes on and off and edit the epigenome in human cells for the first time.

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Duke Engineering News