Eda Yildirim

Assistant Professor of Cell Biology

1. Epigenetic mechanisms regulated by long noncoding RNAs: their regulatory roles in gene expression, genome stability and cell fate decisions.
2. Nuclear structure: its role in gene expression and genome function.

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Affiliate of the Duke Regeneration Center
  • Member of the Duke Cancer Institute

Contact Information

Education

  • Ph.D. University of California, Los Angeles, 2005

Awards, Honors, and Distinctions

  • Whitehead Scholar Award. Duke University. 2014

Courses Taught

  • CELLBIO 493: Research Independent Study

In the News

Representative Publications

  • Yang, T., and E. Yildirim. “Epigenetic and LncRNA-Mediated Regulation of X Chromosome Inactivation and Its Impact on Pathogenesis.” Current Pathobiology Reports 5, no. 1 (March 1, 2017). https://doi.org/10.1007/s40139-017-0120-3.
  • Yildirim, Eda, James E. Kirby, Diane E. Brown, Francois E. Mercier, Ruslan I. Sadreyev, David T. Scadden, and Jeannie T. Lee. “Xist RNA is a potent suppressor of hematologic cancer in mice.” Cell 152, no. 4 (February 14, 2013): 727–42. https://doi.org/10.1016/j.cell.2013.01.034.
  • Yildirim, Eda, Ruslan I. Sadreyev, Stefan F. Pinter, and Jeannie T. Lee. “X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription.” Nat Struct Mol Biol 19, no. 1 (December 4, 2011): 56–61. https://doi.org/10.1038/nsmb.2195.