Josh Huang


Duke School of Medicine Distinguished Professor in Neuroscience

We study the development and function of cortical circuits underlying motor control and cognitive processing. Our research program integrates multi-faceted approaches from genetic engineering to single-cell genomics, developmental neurobiology, imaging, electrophysiology, and behavioral analyses, and aims to link fundamental neuroscience to the understanding and treatment of neuropsychiatric disorders.    

Appointments and Affiliations

  • Duke School of Medicine Distinguished Professor in Neuroscience
  • Professor of Neurobiology
  • Professor of Biomedical Engineering
  • Professor of Cell Biology

Contact Information

  • Office Location: 311 Research Drive, Box 3209, Durham, NC 27710
  • Office Phone: (919) 613-1573
  • Email Address:
  • Websites:


  • Ph.D. Brandeis University, 1995

Awards, Honors, and Distinctions

  • Elected Member. American Academy of Arts & Sciences. 2022

Courses Taught

  • BME 791: Graduate Independent Study
  • NEUROBIO 393: Research Independent Study
  • NEUROBIO 793: Research in Neurobiology

In the News

Representative Publications

  • Qian, Y; Li, J; Zhao, S; Matthews, EA; Adoff, M; Zhong, W; An, X; Yeo, M; Park, C; Yang, X; Wang, B-S; Southwell, DG; Huang, ZJ, Programmable RNA sensing for cell monitoring and manipulation., Nature, vol 610 no. 7933 (2022), pp. 713-721 [10.1038/s41586-022-05280-1] [abs].
  • Huilgol, D; Levine, J; Galbavy, W; Wang, B-S; He, M; Suryanarayana, S; Huang, J, Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types and cortical subnetworks (2022) [10.1101/2022.03.13.484161] [abs].
  • Mohan, H; An, X; Kondo, H; Zhao, S; Matho, K; Musall, S; Mitra, P; Huang, J, Cortical glutamatergic projection neuron types contribute to distinct functional subnetworks (2022) [10.21203/] [abs].
  • Deng, H; Xiao, X; Yang, T; Ritola, K; Hantman, A; Li, Y; Huang, ZJ; Li, B, A genetically defined insula-brainstem circuit selectively controls motivational vigor., Cell, vol 184 no. 26 (2021), pp. 6344-6360.e18 [10.1016/j.cell.2021.11.019] [abs].
  • Dudok, B; Szoboszlay, M; Paul, A; Klein, PM; Liao, Z; Hwaun, E; Szabo, GG; Geiller, T; Vancura, B; Wang, B-S; McKenzie, S; Homidan, J; Klaver, LMF; English, DF; Huang, ZJ; Buzsáki, G; Losonczy, A; Soltesz, I, Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior., Neuron, vol 109 no. 23 (2021), pp. 3838-3850.e8 [10.1016/j.neuron.2021.09.033] [abs].