Kenneth Daniel Poss
James B. Duke Distinguished Professor of Regenerative Biology
Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology
Appointments and Affiliations
- James B. Duke Distinguished Professor of Regenerative Biology
- Professor of Cell Biology
- Director of the Duke Regeneration Center
- Professor in Medicine
- Professor of Biology
- Associate of the Duke Initiative for Science & Society
- Member of the Duke Cancer Institute
Contact Information
- Office Location: 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
- Office Phone: (919) 681-8457
- Email Address: ken.poss@duke.edu
- Websites:
Education
- Children's Hospital, 2003
- University of Utah, 2000
- Ph.D. Massachusetts Institute of Technology, 1998
Awards, Honors, and Distinctions
- Distinguished Achievement Award. Carleton College. 2017
- Merit Award. American Heart Association. 2016
- Ruth and A. Morris Williams Prize in Basic Research. Duke University School of Medicine. 2011
- Early Career Scientist. Howard Hughes Medical Institute. 2009
- Pew Scholars in the Biomedical Sciences. Pew Charitable Trusts, The. 2006
Courses Taught
- BIOLOGY 293: Research Independent Study
- BIOLOGY 314: Regenerative Biology and Medicine
- BIOLOGY 493: Research Independent Study
- BIOLOGY 791T: Tutorial
- CELLBIO 493: Research Independent Study
- CMB 710E: Cell & Molecular Biology Module V
In the News
- Gene Therapy for Heart Attacks in Mice Just Got More Precise (Dec 13, 2022)
- Salamanders Can Regrow Limbs. Why Can't I? (Dec 13, 2019 | School of Medicine)
- Seven From Duke Named Fellows of American Association for the Advancement of Science (Nov 26, 2019)
- Scientists Find Key Protein For Spinal Cord Repair (Nov 3, 2016)
- Study reveals hidden DNA that could be 'reawakened' (Apr 8, 2016 | Daily Mail)
- DNA sequence behind muscle regeneration begins to unravel (Apr 7, 2016 | Gizmag)
- Duke Study Uncovers Genetic Elements That Drive Regeneration (Apr 6, 2016)
- Transgenic zebrafish forms technicolor 'skinbow' (Mar 22, 2016 | Nature)
- Technicolor Zebrafish Reveal How Skin Heals (Mar 21, 2016)
- Duke Study Uncovers Foundations of Heart Regeneration (May 1, 2015)
Representative Publications
- Kikuchi, K; Holdway, JE; Major, RJ; Blum, N; Dahn, RD; Begemann, G; Poss, KD, Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration., Dev Cell, vol 20 no. 3 (2011), pp. 397-404 [10.1016/j.devcel.2011.01.010] [abs].
- Poss, KD, Advances in understanding tissue regenerative capacity and mechanisms in animals., Nat Rev Genet, vol 11 no. 10 (2010), pp. 710-722 [10.1038/nrg2879] [abs].
- Kikuchi, K; Holdway, JE; Werdich, AA; Anderson, RM; Fang, Y; Egnaczyk, GF; Evans, T; Macrae, CA; Stainier, DYR; Poss, KD, Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes., Nature, vol 464 no. 7288 (2010), pp. 601-605 [10.1038/nature08804] [abs].
- Yin, VP; Thomson, JM; Thummel, R; Hyde, DR; Hammond, SM; Poss, KD, Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish., Genes & Development, vol 22 no. 6 (2008), pp. 728-733 [10.1101/gad.1641808] [abs].
- Wills, AA; Holdway, JE; Major, RJ; Poss, KD, Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish., Development (Cambridge, England), vol 135 no. 1 (2008), pp. 183-192 [10.1242/dev.010363] [abs].