Kenneth Daniel Poss


James B. Duke Distinguished Professor of Regenerative Biology

Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Appointments and Affiliations

  • James B. Duke Distinguished Professor of Regenerative Biology
  • Professor of Cell Biology
  • Director of the Duke Regeneration Center
  • Professor in Medicine
  • Professor of Biology
  • Associate of the Duke Initiative for Science & Society
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
  • Office Phone: (919) 681-8457
  • Email Address:
  • Websites:


  • Children's Hospital, 2003
  • University of Utah, 2000
  • Ph.D. Massachusetts Institute of Technology, 1998

Awards, Honors, and Distinctions

  • Distinguished Achievement Award. Carleton College. 2017
  • Merit Award. American Heart Association. 2016
  • Ruth and A. Morris Williams Prize in Basic Research. Duke University School of Medicine. 2011
  • Early Career Scientist. Howard Hughes Medical Institute. 2009
  • Pew Scholars in the Biomedical Sciences. Pew Charitable Trusts, The. 2006

Courses Taught

  • BIOLOGY 293: Research Independent Study
  • BIOLOGY 314: Regenerative Biology and Medicine
  • BIOLOGY 493: Research Independent Study
  • BIOLOGY 791T: Tutorial
  • CELLBIO 493: Research Independent Study
  • CMB 710E: Cell & Molecular Biology Module V

In the News

Representative Publications

  • Kikuchi, K; Holdway, JE; Major, RJ; Blum, N; Dahn, RD; Begemann, G; Poss, KD, Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration., Dev Cell, vol 20 no. 3 (2011), pp. 397-404 [10.1016/j.devcel.2011.01.010] [abs].
  • Poss, KD, Advances in understanding tissue regenerative capacity and mechanisms in animals., Nat Rev Genet, vol 11 no. 10 (2010), pp. 710-722 [10.1038/nrg2879] [abs].
  • Kikuchi, K; Holdway, JE; Werdich, AA; Anderson, RM; Fang, Y; Egnaczyk, GF; Evans, T; Macrae, CA; Stainier, DYR; Poss, KD, Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes., Nature, vol 464 no. 7288 (2010), pp. 601-605 [10.1038/nature08804] [abs].
  • Yin, VP; Thomson, JM; Thummel, R; Hyde, DR; Hammond, SM; Poss, KD, Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish., Genes & Development, vol 22 no. 6 (2008), pp. 728-733 [10.1101/gad.1641808] [abs].
  • Wills, AA; Holdway, JE; Major, RJ; Poss, KD, Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish., Development (Cambridge, England), vol 135 no. 1 (2008), pp. 183-192 [10.1242/dev.010363] [abs].