Kris Cameron Wood

Associate Professor of Pharmacology and Cancer Biology

Appointments and Affiliations

• Associate Professor of Pharmacology and Cancer Biology
• Core Faculty in Innovation & Entrepreneurship
• Member of the Duke Cancer Institute

Contact Information

• Email Address: kris.wood@duke.edu
• Websites:
  • Wood Lab

Education

• Ph.D. Massachusetts Institute of Technology, 2007

Courses Taught

• CMB 710B: Cell & Molecular Biology Module II
• CMB 710E: Cell & Molecular Biology Module V
• MOLCAN 818: Molecular Mechanisms of Oncogenesis
• PHARM 393: Research Independent Study
• PHARM 394: Research Independent Study
• PHARM 493: Research Independent Study
• PHARM 494: Research Independent Study
• PHARM 495: Research Independent Study
• PHARM 818: Molecular Mechanisms of Oncogenesis
• UPGEN 778A: University Program in Genetics and Genomics Biological Solutions Module I

In the News

• Cancer Repair Mechanism Could Be Potential Drug Target (Mar 31, 2022 | Duke Health News)
• Cancer Therapy Using Genetic Targeting and Gel Delivery Shows Promise (Sep 16, 2019 | Pratt School of Engineering)
• From Innovation to Impact (Oct 3, 2018 | Duke Med Alumni News)
• Faculty Startup Sold to Belgian Pharma for $30 Million (Apr 9, 2018)
• Why Do Perfectly Good Cancer Treatments Suddenly Stop Working? (Oct 25, 2017 | Duke Cancer Institute)
• The Challenges of Combating Cancer Drug Resistance (Nov 19, 2015 | Duke Research Blog)
• Researchers Map Paths to Cancer Drug Resistance (Jan 5, 2015)

Representative Publications

• Zhong, Z; Harmston, N; Wood, KC; Madan, B; Virshup, DM, A p300/GATA6 axis determines differentiation and Wnt dependency in pancreatic cancer models., J Clin Invest (2022) [10.1172/JCI156305] [abs].
• Javaid, S; Schaefer, A; Goodwin, CM; Nguyen, VV; Massey, FL; Pierobon, M; Gambrell-Sanders, D; Waters, AM; Lambert, KN; Diehl, JN; Hobbs, GA; Wood, KC; Petricoin, EF; Der, CJ; Cox, AD, Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma., Mol Cancer Ther, vol 21 no. 5 (2022), pp. 762-774 [10.1158/1535-7163.MCT-21-0142] [abs].
• Ali, M; Lu, M; Ang, HX; Soderquist, RS; Eyler, CE; Hutchinson, HM; Glass, C; Bassil, CF; Lopez, OM; Kerr, DL; Falcon, CJ; Yu, HA; Hata, AN; Blakely, CM; McCoach, CE; Bivona, TG; Wood, KC, Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells., Sci Transl Med, vol 14 no. 638 (2022) [10.1126/scitranslmed.abc7480] [abs].
• Wood, KC, Drivers of intrinsic resistance., Nat Chem Biol (2022) [10.1038/s41589-022-00980-1] [abs].
• Garcia, N; Del Pozo, V; Yohe, ME; Goodwin, CM; Shackleford, TJ; Wang, L; Baxi, K; Chen, Y; Rogojina, AT; Zimmerman, SM; Peer, CJ; Figg, WD; Ignatius, MS; Wood, KC; Houghton, PJ; Vaseva, AV, Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma., Mol Cancer Ther, vol 21 no. 1 (2022), pp. 170-183 [10.1158/1535-7163.MCT-21-0194] [abs].