Purushothama Rao Tata

Associate Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Associate Professor of Cell Biology
  • Associate Professor in Medicine
  • Affiliate of the Duke Regeneration Center
  • Member of the Duke Cancer Institute

Contact Information

Education

  • Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

  • Rising Star Award. International Society for Regenerative Biology. 2022
  • Whitehead Scholar Award. Duke University School of Medicine. 2016
  • NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
  • The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

  • PHARM 730: Stem Cell Course
  • MOLCAN 730: Stem Cell Course
  • DSCB 720: Stem Cell Course
  • CMB 720: Modern Techniques in Cell and Molecular Biology
  • CMB 710E: Cell & Molecular Biology Module V
  • CMB 710D: Cell & Molecular Biology Module IV
  • CELLBIO 730: Stem Cell Course
  • CELLBIO 493: Research Independent Study

In the News

Representative Publications

  • Chioccioli, Maurizio, Shuyu Liu, Sumner Magruder, Aleksandra Tata, Lucia Borriello, John E. McDonough, Arvind Konkimalla, et al. “Stem cell migration drives lung repair in living mice.” Dev Cell 59, no. 7 (April 8, 2024): 830-840.e4. https://doi.org/10.1016/j.devcel.2024.02.003.
  • Forrester, Michael T., Jacob R. Egol, Aleksandra Tata, Purushothama Rao Tata, and Matthew W. Foster. “Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap).,” March 27, 2024. https://doi.org/10.1101/2024.03.23.586403.
  • Karmaus, Peer W. F., Aleksandra Tata, Julie M. Meacham, Frank Day, David Thrower, Purushothama Rao Tata, and Michael B. Fessler. “Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates.” Am J Respir Cell Mol Biol 69, no. 6 (December 2023): 623–37. https://doi.org/10.1165/rcmb.2023-0077OC.
  • Vazquez-Armendariz, Ana I., and Purushothama Rao Tata. “Recent advances in lung organoid development and applications in disease modeling.” J Clin Invest 133, no. 22 (November 15, 2023). https://doi.org/10.1172/JCI170500.
  • Konkimalla, Arvind, Satoshi Konishi, Lauren Macadlo, Yoshihiko Kobayashi, Zachary J. Farino, Naoya Miyashita, Léa El Haddad, et al. “Transitional cell states sculpt tissue topology during lung regeneration.” Cell Stem Cell 30, no. 11 (November 2, 2023): 1486-1502.e9. https://doi.org/10.1016/j.stem.2023.10.001.