Eda Yildirim

Assistant Professor of Cell Biology

1. Epigenetic mechanisms regulated by long noncoding RNAs: their regulatory roles in gene expression, genome stability and cell fate decisions.
2. Nuclear structure: its role in gene expression and genome function.

Appointments and Affiliations

• Assistant Professor of Cell Biology
• Member of the Duke Cancer Institute
• Affiliate of the Duke Regeneration Center

Contact Information

• Office Location: DUMC 3709, Nanaline Duke Rm 412A, Durham, NC 27710
• Office Phone: (919) 668-0460
• Email Address: eda.yildirim@duke.edu
• Websites:
  • Duke Cell Biology Department_Yildirim Lab
  • The Yildirim Lab at Duke Cell Biology

Education

• Ph.D. University of California - Los Angeles, 2005

Awards, Honors, and Distinctions

• Whitehead Scholar Award. Duke University. 2014

Courses Taught

• CELLBIO 493: Research Independent Study

In the News

• Eda Yildirim: Solving for X, the Chromosome (Oct 1, 2015)
• Non-coding RNAs: The cancer X factor (Feb 28, 2013 | Nature Review Cancer)

Representative Publications

• Yang, T; Yildirim, E, Epigenetic and LncRNA-Mediated Regulation of X Chromosome Inactivation and Its Impact on Pathogenesis, Current Pathobiology Reports, vol 5 no. 1 (2017) [10.1007/s40139-017-0120-3] [abs].
• Yildirim, E; Kirby, JE; Brown, DE; Mercier, FE; Sadreyev, RI; Scadden, DT; Lee, JT, Xist RNA is a potent suppressor of hematologic cancer in mice., Cell, vol 152 no. 4 (2013), pp. 727-742 [10.1016/j.cell.2013.01.034] [abs].
• Yildirim, E; Sadreyev, RI; Pinter, SF; Lee, JT, X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription., Nat Struct Mol Biol, vol 19 no. 1 (2011), pp. 56-61 [10.1038/nsmb.2195] [abs].