Adjunct Assistant Professor in the Department of Cell Biology
1. Epigenetic mechanisms regulated by long noncoding RNAs: their regulatory roles in gene expression, genome stability and cell fate decisions.
2. Nuclear structure: its role in gene expression and genome function.
Appointments and Affiliations
- Adjunct Assistant Professor in the Department of Cell Biology
- Affiliate of the Duke Regeneration Center
- Member of the Duke Cancer Institute
Contact Information
- Office Location: DUMC 3709, Nanaline Duke Rm 412A, Durham, NC 27710
- Email Address: eda.yildirim@duke.edu
- Websites:
Education
- Ph.D. University of California, Los Angeles, 2005
Awards, Honors, and Distinctions
- Whitehead Scholar Award. Duke University. 2014
Courses Taught
- CELLBIO 493: Research Independent Study
In the News
- Eda Yildirim: Solving for X, the Chromosome (Oct 1, 2015)
- Non-coding RNAs: The cancer X factor (Feb 28, 2013 | Nature Review Cancer)
Representative Publications
- Yang, T., and E. Yildirim. “Epigenetic and LncRNA-Mediated Regulation of X Chromosome Inactivation and Its Impact on Pathogenesis.” Current Pathobiology Reports 5, no. 1 (March 1, 2017). https://doi.org/10.1007/s40139-017-0120-3.
- Yildirim, Eda, James E. Kirby, Diane E. Brown, Francois E. Mercier, Ruslan I. Sadreyev, David T. Scadden, and Jeannie T. Lee. “Xist RNA is a potent suppressor of hematologic cancer in mice.” Cell 152, no. 4 (February 14, 2013): 727–42. https://doi.org/10.1016/j.cell.2013.01.034.
- Yildirim, Eda, Ruslan I. Sadreyev, Stefan F. Pinter, and Jeannie T. Lee. “X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription.” Nat Struct Mol Biol 19, no. 1 (December 4, 2011): 56–61. https://doi.org/10.1038/nsmb.2195.