Professor in Surgery
Synthetic Virology & Gene Therapy
Appointments and Affiliations
- Professor in Surgery
- Director of Gene Therapy
- Professor of Biomedical Engineering
- Professor of Molecular Genetics and Microbiology
- Affiliate of the Duke Regeneration Center
Contact Information
- Office Phone: +1 919 613 6519
- Email Address: aravind.asokan@duke.edu
- Websites:
Education
- Ph.D. University of North Carolina, Chapel Hill, 2004
Research Interests
Virology
RNA Biology
Viral Engineering
RNA Engineering
Gene Therapy
Gene Editing
Gene Regulation
Regenerative Medicine
Courses Taught
- MGM 593: Research Independent Study
- BME 791: Graduate Independent Study
- BME 494: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
In the News
- Duke Companies and Faculty Share Ideas with Investors at Triangle Venture Day (…
- Gene Therapy for Heart Attacks in Mice Just Got More Precise (Dec 13, 2022)
Representative Publications
- Loeb, Ezra J., Patrick L. Havlik, Zachary C. Elmore, Alan Rosales, Sophia M. Fergione, Trevor J. Gonzalez, Timothy J. Smith, Abigail R. Benkert, David N. Fiflis, and Aravind Asokan. “Capsid-mediated control of adeno-associated viral transcription determines host range.” Cell Rep 43, no. 3 (March 26, 2024): 113902. https://doi.org/10.1016/j.celrep.2024.113902.
- Zhu, Xiaoyi, Qiang Huang, Laiming Jiang, Van-Tu Nguyen, Tri Vu, Garth Devlin, Jabbar Shaima, et al. “Longitudinal intravital imaging of mouse placenta.” Sci Adv 10, no. 12 (March 22, 2024): eadk1278. https://doi.org/10.1126/sciadv.adk1278.
- Fiflis, David N., Nicolas A. Rey, Harshitha Venugopal-Lavanya, Beatrice Sewell, Aaron Mitchell-Dick, Katie N. Clements, Sydney Milo, et al. “Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing.” Nat Commun 15, no. 1 (March 14, 2024): 2325. https://doi.org/10.1038/s41467-024-46172-4.
- Kurt, Evan, Garth Devlin, Aravind Asokan, and Tatiana Segura. “Gene Delivery From Granular Scaffolds for Tunable Biologics Manufacturing.” Small, March 11, 2024, e2309911. https://doi.org/10.1002/smll.202309911.
- Barzi, Mercedes, Tong Chen, Trevor J. Gonzalez, Francis P. Pankowicz, Seh Hoon Oh, Helen L. Streff, Alan Rosales, et al. “A humanized mouse model for adeno-associated viral gene therapy.” Nat Commun 15, no. 1 (March 4, 2024): 1955. https://doi.org/10.1038/s41467-024-46017-0.