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Leading in the Development and Application of Genomic Technologies

Realizing the promise of the Genomic Revolution requires a quantum leap in the mechanistic understanding of disease biology and the discovery of drug targets. Remarkable recent innovations such as CRISPR-based genome editing, next-generation DNA sequencing, and high-throughput single-cell genomics have illuminated the path by which a technology-driven approach can inform, streamline, and accelerate drug target discovery. However, a cohesive effort is essential to assimilate these otherwise disparate technologies and disease areas.

The Center for Advanced Genomic Technologies has assembled a team of world-leading engineers, scientists, and physicians to integrate these technologies, adapt them to help unravel disease biology, and discover new drug targets to catalyze a more robust biotechnology enterprise.

In the News

The Duke Center for Advanced Genomic Technologies aims to investigate and re-engineer the inner workings of cellular gene regulation machinery and networks

January 2, 2020 | Duke Engineering News

Duke Researchers Garner Over $6 Million in NIH Funding to Fight Genetic Diseases

Collaborative work using CRISPR genome editing to address the burden of genetic neuromuscular diseases flourishes across Duke.

December 13, 2019 | Duke Engineering News

A Window into the Hidden World of Colons

Combining a skin-level glass window with a gut-stabilizing magnet, researchers get a view into the colon of a live animal

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November 19, 2019

Greg Crawford and Charlie Gersbach Recognized as Highly Cited Researchers

Each year, the Web of Science Group identifies the world’s most influential researchers. The select few who have been most frequently cited by their peers over the last decade. In 2019, fewer than 6,300, or 0.1%, of the world's researchers, across 21 research fields, have earned this exclusive [...]