In the News

Jennifer Doudna holding a model of CRISPR-Cas9

October 25, 2021 | Duke School of Medicine

CRISPR at a Tipping Point: A Q&A with Nobel Laureate Jennifer Doudna

Jennifer Doudna, PhD, professor of chemistry, biochemistry, and molecular biology at the University of California, Berkeley, is a leading figure in the CRISPR revolution. Her fundamental work and leadership in developing the CRISPR-Cas9 genome editing tool earned her and French microbiologist Emmanuelle Charpentier the Nobel Prize in Chemistry in 2020.

i3N iPSC-derived human neurons at 21 DPI. Nuclei are stained with DAPI, neurons are marked by Tubulin, and glutamatergic synapses by PSD95

October 7, 2021

West receives grant from Ruth K. Broad Research Foundation for Alzheimer research

Anne West, MD, PhD, professor of neurobiology, received a Faculty Scholar Award from the Ruth K Broad Biomedical Research Foundation to study noncoding regulation of gene transcription in human neurons. This three-year, $375,000 grant will leverage what researchers already [...]

Charlie Gersbach, Greg Crawford, Tim Reddy, Andrew Allen, David Page, Sayan Mukherjee

September 9, 2021

Two new NIH-funded centers to explore impacts of genomic variation in health, disease

Duke University is the recipient of two large grants totaling nearly $12 million from NHGRI.

PDX1 immunostaining of liver tissue sections at 14 d after injection of mice treated with control and Pdx1-targeted gRNAs. Scale bars, 50 µm.

August 2, 2021

New Mice Enable CRISPR-based Epigenome Editing in Living Animals

A CRISPR-Cas9 variant with deactivated DNA-cutting function – known as “dCas9” - is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations.

Nasdaq highlights Xilis on their tower in Times Square

July 12, 2021 | Duke Translation & Commercialization

Cancer treatment startup started by Duke faculty raises $70M

Charlie Gersbach

June 29, 2021

Gersbach Awarded Distinguished Professorship

Charlie Gersbach has been awarded the John W. Strohbehn Distinguished Professor of Biomedical Engineering, effective July 1, 2021. Appointment to a named chair recognizes excellence in research, teaching and contributions to the university community.  Gerbach is one of 22 [...]

June 16, 2021 | Pratt School of Engineering

Cells Construct Living Composite Polymers for Biomedical Applications

artistic rendering: paper cutout of a head with a puzzle piece taken out

May 6, 2021 | Duke Center for Genomic and Computational Biology

$8M grant aims to better understand disease mechanisms of schizophrenia

A new $8 million NIH grant seeks to uncover more clues into what genes increase the risk of developing schizophrenia.

COVID virus

April 14, 2021 | Duke Today

Duke-Led Team Finds Why Women May Be Better Equipped to Fight COVID

When it comes to COVID-19, women seem to be the stronger sex

three baboons in the wild

April 6, 2021 | Duke Today

A male baboons dominance gives him babies, but costs him years

Struggle for dominance leaves a mark on genes and speeds up aging

Long, thin, well-defined muscle fibers (top left) are in shambles after prolonged inflammation (top right), but maintain their structure (bottom left) and strength (bottom right) when exercised during the inflammation.

January 25, 2021 | Pratt School of Engineering

Exercising Muscle Combats Chronic Inflammation On Its Own

Exercising lab-grown human muscle autonomously blocks the damaging effects of interferon gamma

bacteria tree

January 13, 2021 | Pratt School of Engineering

The Cancer Microbiome Reveals Which Bacteria Live in Tumors

Tissue velocity field and its divergence

January 7, 2021 | Duke Precision Genomics Collaboratory

How does a fish grow back scales?

How does a fish grow back scales it has lost to be the right size? Why don’t they just keep growing? The secret lies in waves of Erk activity.

Clair Engstrom

January 4, 2021 | Duke Research Blog

Claire Engstrom, a Student Researcher Working to Treat Duchenne’s Muscular Dystrophy by Optimizing CRISPR-cas9

Claire first got involved with on-campus research through her pre-orientation program, PSearch.

em cells have the potential to turn into any cell type, which makes them an incredibly powerful tool for disease modeling and regenerative medicine.

December 1, 2020

CRISPR Tagging Improves Accuracy Of Model Cells Grown From Stem Cells

A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.

Astrocytes are highly complex cells that tightly envelope synaptic structures in the brain. This picture shows 3D-printed forms of astrocytes

November 12, 2020 | Duke Today

Astrocytes Identified as Master ‘Conductors’ of the Brain

Star-shaped ‘glue’ cells make it their business to govern connections between neurons

mini lung

October 23, 2020 | Duke Today

Lab-grown Mini-lungs Mimic the Real Thing – Right Down to COVID Infection

Living human lung air sacs in tiny dishes promise to accelerate COVID research

crystal structure of DNA

October 22, 2020 | Duke School of Medicine

Transcription factors may inadvertently lock in DNA mistakes

Transcription factor proteins are the light switches of the human genome.

Yarui Diao

September 23, 2020

Diao receives $3 million grant from 4D Nucleome Consortium

Yarui Diao, Ph.D. received a U01 grant, totaling $3 million in research funding for 5 years, from 4D Nucleome Consortium (phase 2) through the NIH Common fund. Diao aims to determine the function and regulation of high-order chromatin structure on gene regulation and [...]

Purushothama Rao Tata

September 16, 2020 | Duke University

Lung Stem Cells in Transition - a Culprit in Lung Fibrosis

artistic rendering of DNA on black background

September 9, 2020

Diao awarded Genomic Innovator Awards

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, selected Yarui Diao to receive 2020 Genomic Innovator Awards. NHGRI honored a total of 12 early career investigators in genomics.