In the News

Kris Wood

June 6, 2022

Locking Leukemia’s Cellular Escape Hatch

By Alissa Kocer Leukemia starts in cells that would normally develop into different types of blood cells. About 61,000 people in the U.S. are diagnosed each year, and depending on the type of leukemia and the age of the patient, five-year survival rates vary between about [...]

Charlie Gersbach

April 28, 2022 | Gilbert Family Foundation

Gersbach awarded $1.2M Gilbert Family Foundation grant for Gene Therapy Initiative

The Gilbert Family Foundation, announced more than $18 million in grants to fund a new three-year campaign as part of the organization’s Gene Therapy Initiative.

This is a rendering of mRNA, which was successfully used by Emory researchers to modulate gene expression in animal models. The finding could have application for several diseases, including cancer.

April 20, 2022 | Emory News Center

Duke, Emory collaboration successfully uses mRNA to activate genes

What if we could regulate the way genes are expressed? That question has long intrigued researchers, and a new collaboration between Duke and Emory University helps narrow the knowledge gap by showing for the first time that mRNA can be used to activate genes in animals.

IV line with machine in view

March 31, 2022 | Duke Health News

Cancer Repair Mechanism Could Be Potential Drug Target

Disrupting a key cell repair mechanism could extend the benefit of targeted therapies

trainee and mentor standing in front of scientific poster

March 10, 2022

Dedicated to Mentoring

At Duke, mentoring isn't just about trainees' scientific development. Our faculty care about our trainees' growth as individuals too.

duke center for advanced genomic technologies genome technology fellows; two headshots - one woman, one man

February 11, 2022

CAGT names first Genome Technology Fellows

The Center for Advanced Genomic Technologies (CAGT) provided fellowships to support postdoctoral trainees who are conducting research to develop and apply genomic technologies and methods for associated computational analyses to basic and applied biomedical sciences. We [...]

February 11, 2022 | Duke Precision Genomics Collaboratory

Announcing the Genomic Technologies Pilot Grant Winners

February 7, 2022 | Pratt School of Engineering

Tweaked Genes Borrowed From Bacteria Excite Heart Cells in Live Mice

First approach to promote electrical excitation of heart cells in live mammals could lead to new gene therapy treatments for a wide range of heart diseases

Jennifer Doudna holding a model of CRISPR-Cas9

October 25, 2021 | Duke School of Medicine

CRISPR at a Tipping Point: A Q&A with Nobel Laureate Jennifer Doudna

Jennifer Doudna, PhD, professor of chemistry, biochemistry, and molecular biology at the University of California, Berkeley, is a leading figure in the CRISPR revolution. Her fundamental work and leadership in developing the CRISPR-Cas9 genome editing tool earned her and French microbiologist Emmanuelle Charpentier the Nobel Prize in Chemistry in 2020.

i3N iPSC-derived human neurons at 21 DPI. Nuclei are stained with DAPI, neurons are marked by Tubulin, and glutamatergic synapses by PSD95

October 7, 2021

West receives grant from Ruth K. Broad Research Foundation for Alzheimer research

Anne West, MD, PhD, professor of neurobiology, received a Faculty Scholar Award from the Ruth K Broad Biomedical Research Foundation to study noncoding regulation of gene transcription in human neurons. This three-year, $375,000 grant will leverage what researchers already [...]

Charlie Gersbach, Greg Crawford, Tim Reddy, Andrew Allen, David Page, Sayan Mukherjee

September 9, 2021

Two new NIH-funded centers to explore impacts of genomic variation in health, disease

Duke University is the recipient of two large grants totaling nearly $12 million from NHGRI.

PDX1 immunostaining of liver tissue sections at 14 d after injection of mice treated with control and Pdx1-targeted gRNAs. Scale bars, 50 µm.

August 2, 2021

New Mice Enable CRISPR-based Epigenome Editing in Living Animals

A CRISPR-Cas9 variant with deactivated DNA-cutting function – known as “dCas9” - is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations.

Nasdaq highlights Xilis on their tower in Times Square

July 12, 2021 | Duke Translation & Commercialization

Cancer treatment startup started by Duke faculty raises $70M

Charlie Gersbach

June 29, 2021

Gersbach Awarded Distinguished Professorship

Charlie Gersbach has been awarded the John W. Strohbehn Distinguished Professor of Biomedical Engineering, effective July 1, 2021. Appointment to a named chair recognizes excellence in research, teaching and contributions to the university community.  Gerbach is one of 22 [...]

June 16, 2021 | Pratt School of Engineering

Cells Construct Living Composite Polymers for Biomedical Applications

artistic rendering: paper cutout of a head with a puzzle piece taken out

May 6, 2021 | Duke Center for Genomic and Computational Biology

$8M grant aims to better understand disease mechanisms of schizophrenia

A new $8 million NIH grant seeks to uncover more clues into what genes increase the risk of developing schizophrenia.

COVID virus

April 14, 2021 | Duke Today

Duke-Led Team Finds Why Women May Be Better Equipped to Fight COVID

When it comes to COVID-19, women seem to be the stronger sex

three baboons in the wild

April 6, 2021 | Duke Today

A male baboons dominance gives him babies, but costs him years

Struggle for dominance leaves a mark on genes and speeds up aging

Long, thin, well-defined muscle fibers (top left) are in shambles after prolonged inflammation (top right), but maintain their structure (bottom left) and strength (bottom right) when exercised during the inflammation.

January 25, 2021 | Pratt School of Engineering

Exercising Muscle Combats Chronic Inflammation On Its Own

Exercising lab-grown human muscle autonomously blocks the damaging effects of interferon gamma

bacteria tree

January 13, 2021 | Pratt School of Engineering

The Cancer Microbiome Reveals Which Bacteria Live in Tumors

Tissue velocity field and its divergence

January 7, 2021 | Duke Precision Genomics Collaboratory

How does a fish grow back scales?

How does a fish grow back scales it has lost to be the right size? Why don’t they just keep growing? The secret lies in waves of Erk activity.

Clair Engstrom

January 4, 2021 | Duke Research Blog

Claire Engstrom, a Student Researcher Working to Treat Duchenne’s Muscular Dystrophy by Optimizing CRISPR-cas9

Claire first got involved with on-campus research through her pre-orientation program, PSearch.

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