Professor of Computer Science
Computational biology, machine learning, Bayesian statistics, transcriptional regulation, genomics and epigenomics, graphical models, Bayesian networks, hidden Markov models, systems biology, computational neurobiology, classification, feature selection
Appointments and Affiliations
- Professor of Computer Science
- Professor of Biology
- Bass Fellow
Contact Information
- Office Location: 308 Research Drive, LSRC D239, Durham, NC 27708-0129
- Email Address: amink@cs.duke.edu
- Websites:
Education
- B.S. Duke University, 1994
- M.Phil. University of Oxford (United Kingdom), 1996
- Ph.D. Massachusetts Institute of Technology, 2001
Awards, Honors, and Distinctions
- Sloan Research Fellowship-Molecular Biology. Alfred P. Sloan Foundation. 2005
- Faculty Early Career Development (CAREER) Program. National Science Foundation. 2004
Courses Taught
- ETHICS 450S: What Should I Do With My Life? The Art of Choosing Well
- ETHICS 247S: Human Flourishing in a Digital Age
- COMPSCI 394: Research Independent Study
- COMPSCI 393: Research Independent Study
- COMPSCI 260: Introduction to Computational Genomics
- COMPSCI 247S: Human Flourishing in a Digital Age
In the News
- Babs Wise: Paving the Road to a Rhodes (Jan 10, 2022)
- 12 Duke Graduates Named Fulbright Scholars (Feb 22, 2016)
- Genomics Team Wins $5.9 Million Grant (Jan 6, 2015)
- Genes Tell Story of Birdsong and Human Speech (Dec 10, 2014)
- Duke Announces Reorganization of Genome Sciences (Mar 24, 2014)
Representative Publications
- Mitra, Sneha, Rohan Malik, Wilfred Wong, Afsana Rahman, Alexander J. Hartemink, Yuri Pritykin, Kushal K. Dey, and Christina S. Leslie. “Author Correction: Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis.” Nature Genetics 56, no. 6 (June 2024): 1319. https://doi.org/10.1038/s41588-024-01805-8.
- Moyung, Kevin, Yulong Li, Alexander J. Hartemink, and David M. MacAlpine. “Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation.,” May 26, 2024. https://doi.org/10.1101/2024.05.24.595391.
- Mitra, Sneha, Rohan Malik, Wilfred Wong, Afsana Rahman, Alexander J. Hartemink, Yuri Pritykin, Kushal K. Dey, and Christina S. Leslie. “Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis.” Nature Genetics 56, no. 4 (April 2024): 627–36. https://doi.org/10.1038/s41588-024-01689-8.
- Chen, Boning, Heather K. MacAlpine, Alexander J. Hartemink, and David M. MacAlpine. “Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase.” Genome Res 33, no. 12 (December 27, 2023): 2108–18. https://doi.org/10.1101/gr.278273.123.
- Mitra, Sneha, Rohan Malik, Wilfred Wong, Afsana Rahman, Alexander J. Hartemink, Yuri Pritykin, Kushal K. Dey, and Christina S. Leslie. “Single-cell multiome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis.” Cold Spring Harbor Laboratory, June 14, 2023. https://doi.org/10.1101/2023.06.13.544851.