Associate Professor of Neurosurgery
Appointments and Affiliations
- Associate Professor of Neurosurgery
- Associate Professor in Pathology
- Member of the Duke Cancer Institute
Contact Information
- Email Address: anoop.patel@duke.edu
Education
- M.D. Harvard Medical School, 2009
Research Interests
My research lab focuses on using single-cell sequencing techniques to study intratumoral heterogeneity in malignant brain tumors. Intratumoral heterogeneity is the idea that individual cancer cells within a patient’s tumor are different and can respond differently to treatments. I also have an active interest in developing patient-specific models of disease where we can learn how an individual patient's tumor might respond differently than another. My ultimate goal is to further advance precision medicine approaches for malignant brain tumors, and ensure that patients are getting the right treatments for their specific tumors.
Representative Publications
- Murie, Carl, Serdar Turkarslan, Anoop P. Patel, David G. Coffey, Pamela S. Becker, and Nitin S. Baliga. “Individualized dynamic risk assessment and treatment selection for multiple myeloma.” Br J Cancer 132, no. 10 (June 2025): 922–36. https://doi.org/10.1038/s41416-025-02987-6.
- Mihalas, Anca B., Sonali Arora, Samantha A. O’Connor, Heather M. Feldman, Christine E. Cucinotta, Kelly Mitchell, John Bassett, et al. “KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma.” Nat Commun 16, no. 1 (May 9, 2025): 4327. https://doi.org/10.1038/s41467-025-59503-w.
- Isham, Danielle C., Trevor M. Sytsma, Anoop P. Patel, and Vijay K. Ramaiah. “Methadone Analgesia During Awake Craniotomy for a Patient With Chronic Pain on Buprenorphine: A Case Report.” A A Pract 19, no. 4 (April 1, 2025): e01957. https://doi.org/10.1213/XAA.0000000000001957.
- Bomsztyk, Karol, Daniel Mar, Oleg Denisenko, Suzanne Powell, Monika Vishnoi, Zheng Yin, Jennifer Delegard, et al. “Analysis of DNA Methylation in Gliomas: Assessment of Preanalytical Variables.” Lab Invest 104, no. 12 (December 2024): 102160. https://doi.org/10.1016/j.labinv.2024.102160.
- Hotchkiss, Kelly M., Philipp Karschnia, Karisa C. Schreck, Marjolein Geurts, Timothy F. Cloughesy, Jason Huse, Elizabeth S. Duke, et al. “A brave new framework for glioma drug development.” Lancet Oncol 25, no. 10 (October 2024): e512–19. https://doi.org/10.1016/S1470-2045(24)00190-6.