Professor in Surgery
Synthetic Virology & Gene Therapy
Appointments and Affiliations
- Professor in Surgery
- Director of Gene Therapy
- Professor of Biomedical Engineering
- Professor of Molecular Genetics and Microbiology
- Affiliate of the Duke Regeneration Center
Contact Information
- Email Address: aravind.asokan@duke.edu
- Websites:
Education
- Ph.D. University of North Carolina, Chapel Hill, 2004
Research Interests
Virology
RNA Biology
Viral Engineering
RNA Engineering
Gene Therapy
Gene Editing
Gene Regulation
Regenerative Medicine
Courses Taught
- MGM 593: Research Independent Study
- BME 792: Continuation of Graduate Independent Study
- BME 791: Graduate Independent Study
- BME 494: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
In the News
- Duke Companies and Faculty Share Ideas with Investors at Triangle Venture Day (…
- Gene Therapy for Heart Attacks in Mice Just Got More Precise (Dec 13, 2022)
Representative Publications
- Gibson, Rebecca A., William R. Jeck, Rebecca L. Koch, Aarav Mehta, Su Jin Choi, Yajur Sriraman, Deeksha Bali, et al. “Progressive liver disease and dysregulated glycogen metabolism in murine GSD IX γ2 models human disease.” Mol Genet Metab 143, no. 4 (December 2024): 108597. https://doi.org/10.1016/j.ymgme.2024.108597.
- Meganck, Rita M., Roza Ogurlu, Jiacheng Liu, Sven Moller-Tank, Victor Tse, Leo O. Blondel, Alan Rosales, et al. “Sub-genomic flaviviral RNA elements increase the stability and abundance of recombinant AAV vector transcripts.” J Virol 98, no. 8 (August 20, 2024): e0009524. https://doi.org/10.1128/jvi.00095-24.
- Kurt, Evan, Garth Devlin, Aravind Asokan, and Tatiana Segura. “Gene Delivery From Granular Scaffolds for Tunable Biologics Manufacturing.” Small 20, no. 31 (August 2024): e2309911. https://doi.org/10.1002/smll.202309911.
- Yadav, Alka, Rich Liang, Kelly Press, Annika Schmidt, Zahra Shabani, Kun Leng, Calvin Wang, et al. “Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy.” Transl Stroke Res, July 8, 2024. https://doi.org/10.1007/s12975-024-01275-4.
- Smith, Timothy J., Zachary C. Elmore, Robert M. Fusco, Joshua A. Hull, Alan Rosales, Michele Martinez, Alice F. Tarantal, and Aravind Asokan. “Engineered IgM and IgG cleaving enzymes for mitigating antibody neutralization and complement activation in AAV gene transfer.” Molecular Therapy : The Journal of the American Society of Gene Therapy 32, no. 7 (July 2024): 2080–93. https://doi.org/10.1016/j.ymthe.2024.05.004.