Kenneth Daniel Poss

James B. Duke Distinguished Professor of Regenerative Biology

Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Appointments and Affiliations

  • James B. Duke Distinguished Professor of Regenerative Biology
  • Professor of Cell Biology
  • Director of the Duke Regeneration Center
  • Professor of Biology
  • Professor in Medicine
  • Associate of the Duke Initiative for Science & Society
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
  • Office Phone: +1 919 681 8457
  • Email Address:
  • Websites:


  • Ph.D. Massachusetts Institute of Technology, 1998
  • University of Utah, 2000
  • Children's Hospital, 2003

Awards, Honors, and Distinctions

  • Distinguished Achievement Award. Carleton College. 2017
  • Merit Award. American Heart Association. 2016
  • Ruth and A. Morris Williams Prize in Basic Research. Duke University School of Medicine. 2011
  • Early Career Scientist. Howard Hughes Medical Institute. 2009
  • Pew Scholars in the Biomedical Sciences. Pew Charitable Trusts, The. 2006

Courses Taught

  • CMB 710E: Cell & Molecular Biology Module V
  • CELLBIO 493: Research Independent Study
  • BIOLOGY 791T: Tutorial
  • BIOLOGY 493: Research Independent Study
  • BIOLOGY 314: Regenerative Biology and Medicine
  • BIOLOGY 293: Research Independent Study

In the News

Representative Publications

  • Kikuchi, Kazu, Jennifer E. Holdway, Robert J. Major, Nicola Blum, Randall D. Dahn, Gerrit Begemann, and Kenneth D. Poss. “Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration.” Dev Cell 20, no. 3 (March 15, 2011): 397–404.
  • Poss, Kenneth D. “Advances in understanding tissue regenerative capacity and mechanisms in animals.” Nat Rev Genet 11, no. 10 (October 2010): 710–22.
  • Kikuchi, Kazu, Jennifer E. Holdway, Andreas A. Werdich, Ryan M. Anderson, Yi Fang, Gregory F. Egnaczyk, Todd Evans, Calum A. Macrae, Didier Y. R. Stainier, and Kenneth D. Poss. “Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.” Nature 464, no. 7288 (March 25, 2010): 601–5.
  • Yin, Viravuth P., J Michael Thomson, Ryan Thummel, David R. Hyde, Scott M. Hammond, and Kenneth D. Poss. “Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish.” Genes Dev 22, no. 6 (March 15, 2008): 728–33.
  • Wills, Airon A., Jennifer E. Holdway, Robert J. Major, and Kenneth D. Poss. “Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish.” Development 135, no. 1 (January 2008): 183–92.