Associate Professor of Cell Biology
Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology
Appointments and Affiliations
- Associate Professor of Cell Biology
- Associate Professor in Medicine
- Affiliate of the Duke Regeneration Center
- Member of the Duke Cancer Institute
Contact Information
- Email Address: purushothamarao.tata@duke.edu
- Websites:
Education
- Ph.D. University of Ulm (Germany), 2011
Awards, Honors, and Distinctions
- Rising Star Award. International Society for Regenerative Biology. 2022
- Whitehead Scholar Award. Duke University School of Medicine. 2016
- NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
- The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014
Courses Taught
- PHARM 730: Stem Cell Course
- MOLCAN 730: Stem Cell Course
- DSCB 720: Stem Cell Course
- CMB 720: Modern Techniques in Cell and Molecular Biology
- CMB 710E: Cell & Molecular Biology Module V
- CMB 710D: Cell & Molecular Biology Module IV
- CELLBIO 730: Stem Cell Course
- CELLBIO 493: Research Independent Study
In the News
- Study Provides Clues to Developing Better Treatments for Lung Damage (Nov 15, 2…
- Tata to Receive International Society for Regenerative Biology Rising Star Awar…
- NIH-Directors blog- Mini-Lungs in a Lab Dish Mimic Early COVID-19 Infection (No…
- Lab-Grown Mini-Lungs Mimic the Real Thing – Right Down to Covid Infection (Oct …
- SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests (May …
- Scientists Find Stomach Cells In Lung Cancer (Mar 26, 2018)
- Purushothama Tata: So Many Ideas, So Little Time (Oct 2, 2016)
Representative Publications
- Meganck, Rita M., Caitlin E. Edwards, Michael L. Mallory, Rhianna E. Lee, Hong Dang, Alexis B. Bailey, Jason A. Wykoff, et al. “SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia.” Cell Rep 43, no. 4 (April 10, 2024): 114076. https://doi.org/10.1016/j.celrep.2024.114076.
- Chioccioli, Maurizio, Shuyu Liu, Sumner Magruder, Aleksandra Tata, Lucia Borriello, John E. McDonough, Arvind Konkimalla, et al. “Stem cell migration drives lung repair in living mice.” Dev Cell 59, no. 7 (April 8, 2024): 830-840.e4. https://doi.org/10.1016/j.devcel.2024.02.003.
- Forrester, Michael T., Jacob R. Egol, Aleksandra Tata, Purushothama Rao Tata, and Matthew W. Foster. “Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap).,” March 27, 2024. https://doi.org/10.1101/2024.03.23.586403.
- Karmaus, Peer W. F., Aleksandra Tata, Julie M. Meacham, Frank Day, David Thrower, Purushothama Rao Tata, and Michael B. Fessler. “Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates.” Am J Respir Cell Mol Biol 69, no. 6 (December 2023): 623–37. https://doi.org/10.1165/rcmb.2023-0077OC.
- Vazquez-Armendariz, Ana I., and Purushothama Rao Tata. “Recent advances in lung organoid development and applications in disease modeling.” J Clin Invest 133, no. 22 (November 15, 2023). https://doi.org/10.1172/JCI170500.