Adjunct Associate Professor in the Department of Biostatistics & Bioinformatics
Appointments and Affiliations
- Adjunct Associate Professor in the Department of Biostatistics & Bioinformatics
- Associate Professor of Computer Science
- Member of the Duke Cancer Institute
Contact Information
- Office Location: 101 Science Drive, 2179 CIEMAS, Durham, NC 27708
- Email Address: raluca.gordan@duke.edu
- Websites:
Education
- Ph.D. Duke University, 2009
Awards, Honors, and Distinctions
- Sloan Research Fellowship-Molecular Biology. Alfred P. Sloan Foundation. 2014
Courses Taught
- UPGEN 778F: University Program in Genetics and Genomics Biological Solutions Module VI
- COMPSCI 394: Research Independent Study
- COMPSCI 393: Research Independent Study
- CBB 700: Internship
- CBB 591: Independent Study
- CBB 511: Journal Club
- CBB 510S: Computational Biology Seminar
In the News
- A Computer Scientist Investigating the Source Code of Life (Jan 13, 2021 | Duke…
- Transcription Factors May Inadvertently Lock in DNA Mistakes (Oct 21, 2020)
- Five Science Faculty Win Sloan Fellowships (Feb 18, 2014)
Representative Publications
- Duan, Mingrui, Shenghan Song, Hana Wasserman, Po-Hsuen Lee, Ke Jian Liu, Raluca Gordân, Yi He, and Peng Mao. “High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma.” Proc Natl Acad Sci U S A 121, no. 4 (January 23, 2024): e2310854121. https://doi.org/10.1073/pnas.2310854121.
- Martin, Vincentius, Farica Zhuang, Yuning Zhang, Kyle Pinheiro, and Raluca Gordân. “High-throughput data and modeling reveal insights into the mechanisms of cooperative DNA-binding by transcription factor proteins.” Nucleic Acids Res 51, no. 21 (November 27, 2023): 11600–612. https://doi.org/10.1093/nar/gkad872.
- Horton, Connor A., Amr M. Alexandari, Michael G. B. Hayes, Emil Marklund, Julia M. Schaepe, Arjun K. Aditham, Nilay Shah, et al. “Short tandem repeats bind transcription factors to tune eukaryotic gene expression.” Science 381, no. 6664 (September 22, 2023): eadd1250. https://doi.org/10.1126/science.add1250.
- Glasscock, Cameron J., Robert Pecoraro, Ryan McHugh, Lindsey A. Doyle, Wei Chen, Olivier Boivin, Beau Lonnquist, et al. “Computational design of sequence-specific DNA-binding proteins.” BioRxiv, September 21, 2023. https://doi.org/10.1101/2023.09.20.558720.
- Mielko, Zachery, Yuning Zhang, Harshit Sahay, Yiling Liu, Matthew A. Schaich, Brittani Schnable, Abigail M. Morrison, et al. “UV irradiation remodels the specificity landscape of transcription factors.” Proc Natl Acad Sci U S A 120, no. 11 (March 14, 2023): e2217422120. https://doi.org/10.1073/pnas.2217422120.