Purushothama Rao Tata
Assistant Professor of Cell Biology
Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology
Appointments and Affiliations
- Assistant Professor of Cell Biology
- Assistant Professor in Medicine
- Member of the Duke Cancer Institute
- Affiliate of the Duke Regeneration Center
Contact Information
- Email Address: purushothamarao.tata@duke.edu
- Websites:
Education
- Ph.D. University of Ulm (Germany), 2011
Courses Taught
- CELLBIO 493: Research Independent Study
- CELLBIO 730: Stem Cell Course
- CMB 710D: Cell & Molecular Biology Module IV
- MOLCAN 730: Stem Cell Course
- PHARM 730: Stem Cell Course
In the News
- NIH-Directors blog- Mini-Lungs in a Lab Dish Mimic Early COVID-19 Infection (Nov 19, 2020 | NIH-Directors blog)
- Lab-Grown Mini-Lungs Mimic the Real Thing – Right Down to Covid Infection (Oct 22, 2020)
- SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests (May 11, 2020 | www.hhmi.org)
- Scientists Find Stomach Cells In Lung Cancer (Mar 26, 2018)
- Purushothama Tata: So Many Ideas, So Little Time (Oct 2, 2016)
Representative Publications
- Leinroth, AP; Mirando, AJ; Rouse, D; Kobayahsi, Y; Tata, PR; Rueckert, HE; Liao, Y; Long, JT; Chakkalakal, JV; Hilton, MJ, Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations., Cell Reports, vol 39 no. 6 (2022) [10.1016/j.celrep.2022.110785] [abs].
- Kadur Lakshminarasimha Murthy, P; Sontake, V; Tata, A; Kobayashi, Y; Macadlo, L; Okuda, K; Conchola, AS; Nakano, S; Gregory, S; Miller, LA; Spence, JR; Engelhardt, JF; Boucher, RC; Rock, JR; Randell, SH; Tata, PR, Human distal lung maps and lineage hierarchies reveal a bipotent progenitor., Nature, vol 604 no. 7904 (2022), pp. 111-119 [10.1038/s41586-022-04541-3] [abs].
- Kadur Lakshminarasimha Murthy, P; Xi, R; Arguijo, D; Everitt, JI; Kocak, DD; Kobayashi, Y; Bozec, A; Vicent, S; Ding, S; Crawford, GE; Hsu, D; Tata, PR; Reddy, T; Shen, X, Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity., Dev Cell, vol 57 no. 3 (2022), pp. 310-328.e9 [10.1016/j.devcel.2022.01.006] [abs].
- Kumar, V; Madhurakkat Perikamana, SK; Tata, A; Hoque, J; Gilpin, A; Tata, PR; Varghese, S, An In Vitro Microfluidic Alveolus Model to Study Lung Biomechanics., Frontiers in Bioengineering and Biotechnology, vol 10 (2022) [10.3389/fbioe.2022.848699] [abs].
- Konkimalla, A; Tata, A; Tata, PR, Lung Regeneration: Cells, Models, and Mechanisms., Cold Spring Harbor Perspectives in Biology (2021) [10.1101/cshperspect.a040873] [abs].